Human Growth Foundation
997 Glen Cove Avenue, Suite 5
Glen Head, NY 11545

T1-800-451-6434
F1-516-671-4055

E-Mail Contacts

images/template/little_arrow.gifExecutive Director
images/template/little_arrow.gifWebmaster
images/template/little_arrow.gifFeedback

Resources

images/template/little_arrow.gifDisorders of Short Stature
images/template/little_arrow.gifPediatric Growth Hormone Deficiency
images/template/little_arrow.gifAdult Growth Hormone Deficiency
images/template/little_arrow.gifResearchers Corner
images/template/little_arrow.gifPatients Corner
images/template/little_arrow.gifrGH Pharmaceutical Manufacturers
images/template/little_arrow.gifLinks to Organizations & Information
images/template/little_arrow.gifClinical Trials and Studies
images/template/little_arrow.gifMedical Insurance Issues


Support for Children & Adults

images/template/little_arrow.gifPediatric Discussion Forum
images/template/little_arrow.gifAdult Discussion Forum


HGF Programs

images/template/little_arrow.gifAnnual Research Grant Program
images/template/little_arrow.gifHGF Gift Giving Program


HGF Publications

images/template/little_arrow.gifShort and OK
images/template/little_arrow.gifReady for School
images/template/little_arrow.gifPatterns of Growth
images/template/little_arrow.gifGrowth Hormone Deficiency
images/template/little_arrow.gifTurner Syndrome
images/template/little_arrow.gifread more


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patients CORNER
(Patient Information for the Layperson)

INTRODUCTION

CHILDREN'S CORNER

ADULTS CORNER

WANT TO KNOW MORE?


INTRODUCTION

What Patients Corner Is

As contrasted with Researchers Corner, which contains medical information gleaned from medical studies and literature, Patients Corner contains significant information gleaned from patients, concerning the current practice of endocrine and metabolic medicine as it relates to adults and parents of children with disorders of growth, growth hormone, and related endocrine issues.

Patients Corner is focused on the diagnosis and treatment of the individual patient; whereas Researchers Corner is focused on the development of evidence-based medicine from which to derive standard criteria for diagnosis and treatment.

Patients Corner captures practical information, which may not not yet be published, for immediate use by patients for discussion with their endocrinologists. It is anticipated that entries to this page will be intermittent and relatively sparse; but, that the content of the page will be noteworthy.

Caveat: By nature, the content of Patients Corner may be anecodotal and not applicable to other patients. The accounts of diagnsosis and treatment may be inaccurate; or may work out without any fault involved. No identity or contact information is disclosed or published.

How to Get a Story Published in Patients Corner

iIf you are or a parent of a child who is a patient;, or are an adult patient; and, have an account relating to the diagnosis or treatment of a disorder of growth, growth hormone, or related endocrine issue, which you believe is new or novel, please submit it the Webmaster for review and consideration for publication in Patients Corner at the discretion of the Webmaster. All contact and source information confidential and held in strict confidence; and, none will be published. However, please do not submt any account that includes a complaint of any kind because it will not considered or published on this Website. Publication is within the sole descretion of the Webmaster and HGF.

CHILDREN'S CORNER

Use of Arimidex in Puberty

Pediatric endocrinolgist extended the use of Arimidex (anastrozole), an aromatase inhibitor (AI), beyond 2.5 years for a short period of time, with close monitoring. The reason for its use beyond one to two years was based on significant rate of growth with rhGH, and absence of any signs or symptoms that suggest any adverse event arising from its use.

The purpose of using an AI is to (1) suppress acceleration of bone age and fusion of the epiphyses and growth plates of the skeletal long bones, and (2) allow the development of secondary sex characteristics in males, while at the same time suppressing estradiol. Estradiol is an estrogen, which causes acceleration of bone age and fusion of the epiphysis and growth plates, thus advancing the end of puberty in boys and girls (published January 27, 2008).

ADULTS CORNER

(No entries)

WANT TO KNOW MORE?

Do you wish additional information, want the information you have read explained, or desire to know how it applies to your child, or to you, an adult? Join the HGF Peds Discussion Forum or the HGF Adults Discussion Forum, respectively.

   
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copyright ©  Human Growth Foundation, all rights reserved.
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O



Human Growth Foundation
997 Glen Cove Avenue, Suite 5
Glen Head, NY 11545

T 1-800-451-6434
F 1-516-671-4055

E-Mail Contacts

images/template/little_arrow.gifExecutive Director
images/template/little_arrow.gifWebmaster
images/template/little_arrow.gifFeedback

Resources

images/template/little_arrow.gifDisorders of Short Stature
images/template/little_arrow.gifPediatric Growth Hormone Deficiency
images/template/little_arrow.gifAdult Growth Hormone Deficiency
images/template/little_arrow.gifResearchers Corner
images/template/little_arrow.gifPatients Corner
images/template/little_arrow.gifrGH Pharmaceutical Manufacturers
images/template/little_arrow.gifLinks to Organizations & Information
images/template/little_arrow.gifTests, Studies & Clinical Trials


Support for Children & Adults

images/template/little_arrow.gifPediatric Discussion Forum
images/template/little_arrow.gifAdult Discussion Forum


HGF Programs

images/template/little_arrow.gifAnnual Research Grant Program
images/template/little_arrow.gifHGF Gift Giving Program


HGF Publications

images/template/little_arrow.gifShort and OK
images/template/little_arrow.gifReady for School
images/template/little_arrow.gifPatterns of Growth
images/template/little_arrow.gifGrowth Hormone Deficiency
images/template/little_arrow.gifTurner Syndrome
images/template/little_arrow.gifread more


MEMBERSHIP AND DONATIONS
PAY ON-LINE WITH PAYPAL
It's fast, free and secure!


A PayPal account is not required.
All major credit cards are accepted.
Simply click the "Donate" button below.

https://www.paypal.com/en_US/i/scr/pixel.gif


To join now click here.


images/template/medinex_logo.gif

 

Recent News

Conditional Cardiovascular Response to Growth Hormone Therapy in Adult Patients with Prader-Will Syndrome (PWS)
On January 20, 2007, clinical investigators in Italy reported that altered GH secretion has been related to reduced cardiac mass and function. Upon evaluating cardiovascular response to GH secretion in PWS adults, they found that GH therapy increased cardiac mass without disastolic consequences; but they observed a slight deterioration of right heart function and an association between IGF-I and left-venricular function, which they concluded requires appropriate cardiac and hormonal monitoring . Reported in the Journal of Clinical Endocrinology and Metabolism, April 2007, 92(4):1364-1371.

Consensus Statement: Management of Children Born Small-for-Gesational Age (SGA) through Adulthood
On January 2, 2007, the International Societies of Pediatric Endocrinology and the Growth Hormone Research Society issued a consensus statement containing the following conclusions: The diagnosis of SGA should be based on accurate birth measurements for weight, length, and head circumference. There should be early surveillance in growth clinics for the children without catch-up growth; and, early neurodevelopment evaluation and intervention for at-risk children. For the 10 percent of SGA children who lack catch up growth, growth hormone (rhGH) can increase linear growth. Long term surveillance of treated children is required. Associations between low birth weight, including SGA, and coronary heart disease and stroke in later life are recognized, but there is presently insufficient evidence to recommend surveillance of all adults born SGA. Reported in the Journal of Endocrinology and Metabolism, March 2007, 92(3):804-810.

Clinical Practice Guideline: Care of Girls and Women with Turner Syndrome (TS)
On October 25, 2006, The Turner Syndrome Consensus Study Group, consisting of an international group of premier endocrinologists in the area of TS, issued a "Guideline" for the care of girls and women with TS. The Guidelines highlight the need for diagnosis, monitoring, and preventative care relating to cardiovascular defects; early identification of potential attention-deficit or non-verbal learning disorders; lifetime monitoring of hearing and thyroid hormone funcction; and the monitoring of adults for aortic enlargement, hypertension, diabetes, and dyslipidemia; open discussion of premature ovarian failure and the importance of estrogen treatment for feminization and bone health. The Study Group also recommended that puberty should not be delayed to promote statural growth; but recognized that most girls with TS are now treated with growth hormone. Reported in the Journal of Endocrinology and Metabolism, January 2007, 92(1):10-25.

Growth with Growth Hormone in Short Stature Children
On October 18, 2005, Newsday.com, published the following article by Ellen Mitchell, a free lance reporter, entitled "A Tall Order: For some short children growth hormones are the answer." In the article, Ms. Mitchell tells of the use of recombinant (biosynthetic) growth hormone in children with short stature to achieve growth, highlighting issues and personal success stories involved in growth hormone replacement therapy.

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FDA Approves Expanded Use of rGH
On July 26, 2003, the federal Food and Drug Administration approved a supplemental new drug application by Eli Lilly & Company for the use of recombinant human growth hormone to treat children who are healthy but unusually short (defined as an adult height of less than 5 feet 3 inches for men and 4 feet 11 inches for women) without a known cause.

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International Consensus on Deficiency & Management of SGA with rGH
Pfizer has announced in the June 2003 issue of Pediatrics, the official journal of the American Academy of Pediatrics, the publication of an international consensus statement on the Deficiency and management of persistent short stature in children born small for gestational age (SGA) who do not exhibit catch-up growth by age two.

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FDA Advisory Committee Recommends FDA approval of Expanded Use of rGH
Application (sNDA) by Eli Lilly and Company for recombinant growth hormone for non-GHD boys and girls who are exceedingly short stature, and who are not likely to reach a reasonably normal adult height. Nicole Costa, daughter of Patricia D (Patti) Costa, Executive Director of HGF, and Patti Costa, testified in favor of the sNDA.

read more
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copyright ©  Human Growth Foundation, all rights reserved.
Website by Association Web Services.com