Human Growth Foundation
997 Glen Cove Avenue, Suite 5
Glen Head, NY 11545

T1-800-451-6434
F1-516-671-4055

E-Mail Contacts

images/template/little_arrow.gifExecutive Director
images/template/little_arrow.gifWebmaster
images/template/little_arrow.gifFeedback

Resources

images/template/little_arrow.gifDisorders of Short Stature
images/template/little_arrow.gifPediatric Growth Hormone Deficiency
images/template/little_arrow.gifAdult Growth Hormone Deficiency
images/template/little_arrow.gifResearchers Corner
images/template/little_arrow.gifPatients Corner
images/template/little_arrow.gifrGH Pharmaceutical Manufacturers
images/template/little_arrow.gifLinks to Organizations & Information
images/template/little_arrow.gifClinical Trials and Studies
images/template/little_arrow.gifMedical Insurance Issues


Support for Children & Adults

images/template/little_arrow.gifPediatric Discussion Forum
images/template/little_arrow.gifAdult Discussion Forum


HGF Programs

images/template/little_arrow.gifAnnual Research Grant Program
images/template/little_arrow.gifHGF Gift Giving Program


HGF Publications

images/template/little_arrow.gifShort and OK
images/template/little_arrow.gifReady for School
images/template/little_arrow.gifPatterns of Growth
images/template/little_arrow.gifGrowth Hormone Deficiency
images/template/little_arrow.gifTurner Syndrome
images/template/little_arrow.gifread more


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RESEARCHERS CORNER
(Medical Information for the Layperson)

INTRODUCTION

What Researchers Corner Is

Reseachers' Corner is a medical information resource that consists of medical information collected from various high quality, mainstream medical and scientific papers, journals, textbooks, and organizations.

Researchers' Corner is designed to present to interested laypersons reasonably current, timely, and accurate medical information on disorders of growth, growth hormone; and, related endocrine disorders, diseases, syndromes, conditions, and diagnoses.

The purpose of the Researchers' Corner is to provide medical information to adults and to the parents andr guardians of children to help them to understand the medical vocabulary and principals of medicine involved in addressing and discussing those those medical concerns with their endocrinologists.

What Researchers Corner Is Not

Researchers' Corner is not intended (1) for the practice of medicine; (2) to be a physician's reference; or, (3) to supplant medical information, opinion, guidance, or patient management , which includes treatment prescribed by a physician for a patient. Each patient has his or her own medical context and diagnosis(es), which is solely for the physician to determine and and treat.

As in most medical areas within mainstream medicine, there can be differing, but acceptable views and approaches to diagnosis and patient managment. In part, those differences occur because of the constantly developing knowledge base of medicine, which inherently involves change from study to study. Ultimately, those differences are often resolved in consensus statements and guidelines, which influence, and helps to make uniform standards of care throughtout the States of the United States, and various countries and other political entities throughout the world.

Organization and Presentation of the Information

Researcher's Corner is organized into three main subject groups: (1) Pediatrics, (2) Adults, and (3) Other. Within each of those groups, the information is grouped by medical disorder, disease, syndrome, condition or diagnosis.

The information presented in Researchers' Corner will usually be in the form of abstract snippets. "Abstracts" are short summaries of the purpose, methods, findings or results, and conclusion of studies, reports, commentaries, or papers (collectively "Work" or Works." "Snippets" are portions of abstracts. In some instances the snippet will be a quotation from the abstract. In other instances, it will be paraphrased or a combination thereof. The information may include editorial comment by the HGF Webmaster, where appropriate for context or clarity.

The information may contain work product by authors and publishers that is subject to the Copyright Act of 1976, effective on January 1, 1978 (17 U.S.C. § 101), as amended.  The use of this work product for non-commercial, educational purposes in Researchers' Corner, is legally permitted pursuant to the fair use" exception of the United States Copyright Act (17 U.S.C. § 107). 

How to Read a Study, Report, Commentary or Other Paper

Read a study or abstract in the order given below, which starts with an overview of the study, which is reasonably understandable, to very specific information that may be less than reseaonably understandable to the layperson.

1. The title, the names, institutions or facilties for whom they work, the name of the name of the j    journal in which the study is published, the sponsors of the study, and the date the study     was published.

2. The introduction or summary that states the purpose of the study and may provide brief     background information, which is at the beginning of the study.

3. The conclusory paragraphs at the end of the study of the study.

4. The discussion,which is in the middle of the study.

5. The results or findings of the studies.

6 The detail of the protocol, methods, procedures, and data from which the results or findings
    were generated.

How to Evaluate a Study, Report, Commentary, or other Paper

iIn the medical area, many studies, reports, commentaries, or papers are published by or on behalf of various medical and scientific organizations, and with funding from the Federal government and the private sector that encompass the subject matter of the study. Some of the organizations establish standards and criteria for the submission of works for publication. They also have editors and may have decision-making bodies tha t make decisions on accepting, editing, and publishing Works. Many of journals include provisions for peer review and comment.

IImportant considerations in evaluating the accuracy, credability, and trustworthiness of a Work include the following:

1. The competence, experience, stature of the researchers and authors of the works within the      medical specialty of the works.

2. The reputation of the journals within the medical community that publish the works.

3. The sponsors of the works.

4. The purpose and scope of the work; adequacy of the protocol, procedures, methods;     equipment to accomplish the purpose of the work.

5. Whether the results or findings of the work support the conclusions of the work; and,     whether the conclusions satisfactorily address the purpose of the work.

6. The adequacy and clarity of the presentation of any medical literature that is necessary to     support to support the findings, analysis, and conclusions of the work.

7. The findings and conclusions of contained in other works that have addressed same, similar     or related issues.

8. Also, look for, and compare and contrast for, trends, consistency and inconsistencies in the conclusions of Works; and, for the same authors or investigators appearing in the Works.

Want to Know More?

Do you wish additional information, want the information you have read explained, or desire to know how it applies to your child, or to you, and adult? Join the HGF Peds Discussion Forum or the HGF Adults Discussion Forum, respectively.

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copyright ©  Human Growth Foundation, all rights reserved.
Website by Association Web Services.com

O



Human Growth Foundation
997 Glen Cove Avenue, Suite 5
Glen Head, NY 11545

T 1-800-451-6434
F 1-516-671-4055

E-Mail Contacts

images/template/little_arrow.gifExecutive Director
images/template/little_arrow.gifWebmaster
images/template/little_arrow.gifFeedback

Resources

images/template/little_arrow.gifDisorders of Short Stature
images/template/little_arrow.gifPediatric Growth Hormone Deficiency
images/template/little_arrow.gifAdult Growth Hormone Deficiency
images/template/little_arrow.gifResearchers Corner
images/template/little_arrow.gifPatients Corner
images/template/little_arrow.gifrGH Pharmaceutical Manufacturers
images/template/little_arrow.gifLinks to Organizations & Information
images/template/little_arrow.gifTests, Studies & Clinical Trials


Support for Children & Adults

images/template/little_arrow.gifPediatric Discussion Forum
images/template/little_arrow.gifAdult Discussion Forum


HGF Programs

images/template/little_arrow.gifAnnual Research Grant Program
images/template/little_arrow.gifHGF Gift Giving Program


HGF Publications

images/template/little_arrow.gifShort and OK
images/template/little_arrow.gifReady for School
images/template/little_arrow.gifPatterns of Growth
images/template/little_arrow.gifGrowth Hormone Deficiency
images/template/little_arrow.gifTurner Syndrome
images/template/little_arrow.gifread more


MEMBERSHIP AND DONATIONS
PAY ON-LINE WITH PAYPAL
It's fast, free and secure!


A PayPal account is not required.
All major credit cards are accepted.
Simply click the "Donate" button below.

https://www.paypal.com/en_US/i/scr/pixel.gif


To join now click here.


images/template/medinex_logo.gif

 

Recent News

Conditional Cardiovascular Response to Growth Hormone Therapy in Adult Patients with Prader-Will Syndrome (PWS)
On January 20, 2007, clinical investigators in Italy reported that altered GH secretion has been related to reduced cardiac mass and function. Upon evaluating cardiovascular response to GH secretion in PWS adults, they found that GH therapy increased cardiac mass without disastolic consequences; but they observed a slight deterioration of right heart function and an association between IGF-I and left-venricular function, which they concluded requires appropriate cardiac and hormonal monitoring . Reported in the Journal of Clinical Endocrinology and Metabolism, April 2007, 92(4):1364-1371.

Consensus Statement: Management of Children Born Small-for-Gesational Age (SGA) through Adulthood
On January 2, 2007, the International Societies of Pediatric Endocrinology and the Growth Hormone Research Society issued a consensus statement containing the following conclusions: The diagnosis of SGA should be based on accurate birth measurements for weight, length, and head circumference. There should be early surveillance in growth clinics for the children without catch-up growth; and, early neurodevelopment evaluation and intervention for at-risk children. For the 10 percent of SGA children who lack catch up growth, growth hormone (rhGH) can increase linear growth. Long term surveillance of treated children is required. Associations between low birth weight, including SGA, and coronary heart disease and stroke in later life are recognized, but there is presently insufficient evidence to recommend surveillance of all adults born SGA. Reported in the Journal of Endocrinology and Metabolism, March 2007, 92(3):804-810.

Clinical Practice Guideline: Care of Girls and Women with Turner Syndrome (TS)
On October 25, 2006, The Turner Syndrome Consensus Study Group, consisting of an international group of premier endocrinologists in the area of TS, issued a "Guideline" for the care of girls and women with TS. The Guidelines highlight the need for diagnosis, monitoring, and preventative care relating to cardiovascular defects; early identification of potential attention-deficit or non-verbal learning disorders; lifetime monitoring of hearing and thyroid hormone funcction; and the monitoring of adults for aortic enlargement, hypertension, diabetes, and dyslipidemia; open discussion of premature ovarian failure and the importance of estrogen treatment for feminization and bone health. The Study Group also recommended that puberty should not be delayed to promote statural growth; but recognized that most girls with TS are now treated with growth hormone. Reported in the Journal of Endocrinology and Metabolism, January 2007, 92(1):10-25.

Growth with Growth Hormone in Short Stature Children
On October 18, 2005, Newsday.com, published the following article by Ellen Mitchell, a free lance reporter, entitled "A Tall Order: For some short children growth hormones are the answer." In the article, Ms. Mitchell tells of the use of recombinant (biosynthetic) growth hormone in children with short stature to achieve growth, highlighting issues and personal success stories involved in growth hormone replacement therapy.

read more

FDA Approves Expanded Use of rGH
On July 26, 2003, the federal Food and Drug Administration approved a supplemental new drug application by Eli Lilly & Company for the use of recombinant human growth hormone to treat children who are healthy but unusually short (defined as an adult height of less than 5 feet 3 inches for men and 4 feet 11 inches for women) without a known cause.

read more

International Consensus on Deficiency & Management of SGA with rGH
Pfizer has announced in the June 2003 issue of Pediatrics, the official journal of the American Academy of Pediatrics, the publication of an international consensus statement on the Deficiency and management of persistent short stature in children born small for gestational age (SGA) who do not exhibit catch-up growth by age two.

read more

FDA Advisory Committee Recommends FDA approval of Expanded Use of rGH
Application (sNDA) by Eli Lilly and Company for recombinant growth hormone for non-GHD boys and girls who are exceedingly short stature, and who are not likely to reach a reasonably normal adult height. Nicole Costa, daughter of Patricia D (Patti) Costa, Executive Director of HGF, and Patti Costa, testified in favor of the sNDA.

read more
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copyright ©  Human Growth Foundation, all rights reserved.
Website by Association Web Services.com